Pentobarbital will decrease the level or effect of fostemsavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. pentobarbital will decrease the level or effect of quinine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of cevimeline by affecting hepatic/intestinal enzyme CYP... https://trackbookmark.com/story22018786/the-ultimate-guide-to-pentobarbital-de-sodium