Adenosine acting in the basal forebrain is a key mediator of sleep homeostasis. Extracellular adenosine concentrations increase during wakefulness. especially during prolonged wakefulness and lead to increased sleep pressure and subsequent rebound sleep. The release of endogenous adenosine during the sleep-wake cycle has mainly been studied in vivo with microdialysis techniques. https://www.roneverhart.com/Craggy-Range-Sauvignon-Blanc-Te-Muna-Road-Vineyard-Martinborough-2022/