two. Histamine Receptor Antagonism: Some sedatives, for instance antihistamines, exert their sedative effects by blocking histamine receptors within the brain, especially H1 receptors. Histamine plays a job in wakefulness and arousal, so blocking its effects promotes sedation and sleepiness. Don’t mix sedatives alongside one another or with other drugs https://sedativesdrugs19641.blogvivi.com/33669154/common-sedation-drugs-used-in-icus-essential-medications-guide