At three times submit-MPTP, we identified major microglial activation and up-regulation of CB2 cannabinoid receptors while in the ventral midbrain. Remedy with Gain or the CB2 receptor agonist JWH015 (4 mg/kg, intraperitoneal) lowered MPTP-induced microglial activation, While genetic ablation of CB2 receptors exacerbated MPTP systemic toxicity. On top of that, https://win55.clinic/tin-tuc